Oily fish 'can increase brain size'
EATING more oily fish can increase brain size in later life and may help prevent age-related mental decline, a study has found.
People with higher levels of omega-3 fatty acids found in fish oil preserve bigger brains as they age, the research shows.
In particular, they maintain more nerve cells in the hippocampus, the brain's key memory centre.
The
larger neural volume linked to omega-3 intake is equivalent to reducing
the effects of brain ageing by up to two years, say scientists.
Researchers measured levels of two essential omega-3 fatty acids, EPA
and DHA, in the blood of 1,111 women taking part in the US Women's
Health Initiative Memory Study.
Eight years later, when the women
had an average age of 78, magnetic resonance imaging (MRI) scans were
performed to measure their brain size.
Those who started out with higher intakes of omega-3 were found to have larger total brain volumes.
A doubling of omega-3 levels was associated with a 0.7 per cent increase in overall brain size.
In addition, the hippocampus area was 2.7 per cent larger in women with higher levels of the fatty acids.
Lead
scientist Dr James Pottala, from the University of South Dakota in
Sioux Falls, US, said: "These higher levels of fatty acids can be
achieved through diet and the use of supplements, and the results
suggest that the effect on brain volume is the equivalent of delaying
the normal loss of brain cells that comes with ageing by one to two
years."
The findings are published in the latest online edition of the journal Neurology.
Shrinking brain volume is a known sign of Alzheimer's disease as well as normal ageing.
Dr
Laura Phipps, from the charity Alzheimer's Research UK, said: "There
has been mixed evidence as to the benefits of omega-3 fish oils on the
brain and whether they may protect against memory decline and dementia.
"This
study suggests that higher levels of omega-3 fatty acids in blood are
linked to larger brain size but the possible reasons for this
association need further investigation.
"We know that the brain
gets smaller in people with dementia, but it is unclear from the study
what effect larger brain size would have on memory and thinking in the
volunteers or their long-term risk of developing dementia," Phipps said.
"The
best way to assess whether omega-3 could protect against dementia is
through clinical trials and so far, trials of omega-3 supplementation
have not shown benefits in protecting against cognitive decline."
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